Great answers. Drinking alcohol is part of our culture. I’m certain that it won’t stop, it’s to big of a business! LaRue said it first–moderation.
Karin’s point is especially important. Ethanol, and its first metabolite, acetaldehyde, are containdicated with many different medications, antidepressants in particular.
The calories added with mixers can certainly be a concern for those interested in losing weight.
I think that, in general, one drink a day for both men and women should be reasonable. More than that, unreasonable.