I have both an in-home business and do some training at a local community center. I can’t say this is really a struggle, but it does take more time to travel between homes (as opposed to the Rec center where I book multiple clients back to back).
The only other issue for me is that in-home is a little harder to find clients–at the Rec where I work many people know me and I get referrals. That being said, I do not advertise my in-home at all outside of my website and FB account and here on IDEA.
I do well with referrals, and the clients I’ve gotten from IDEA are long-term (I work part-time about 25 hours per week).
So, these are the biggest things for me, but not really struggles as I love it all.