Mind-Body Lifestyle Changes Impact Cancer Genes
If the genetic cards are stacked against you, do not give up hope. Intensive lifestyle changes may be able to influence powerful genetic factors, according to recent studies. Dean Ornish, MD, president of the Preventive Medicine Research Institute and a clinical professor of medicine at the University of California, San Francisco, led a team of researchers investigating the impact of an intensive nutrition and lifestyle intervention on men with low-risk prostate cancer.
The scientists compared gene expression profiles from 30 male participants with prostate cancer before and after a vigorous 3-month program of dietary change, moderate exercise, stress management and group support. All participants had low-risk prostate cancer and had refused immediate surgery, hormone therapy or radiation; instead, they elected to participate in the lifestyle program, which included periodic monitoring of tumors to track any growth.
Program participants followed a vegan diet; walked 30 minutes a day, 6 days a week; and practiced stress management, consisting of yoga-based stretching, breathing, meditation, imagery and progressive relaxation. Subjects also took daily supplements of soy, fish oil, vitamin E, selenium and vitamin C. After 3 months, the researchers observed changes in gene expression that affected the tumors: genes that promoted the cancer were no longer active or were less active, and genes that helped fight the cancer were switched on.
“I thought younger people with milder disease would show the most improvement, but neither age nor disease severity made as much difference as adherence [to the program],” Ornish told HealthDay. That means that the more people are able to change, the better. And these findings suggest that you’re never too old to make changes that can positively affect your health.”
The study was published in the Proceedings of the National Academy of Sciences (2008; 105 ; 8369-74).
For the latest research, statistics, sample classes, and more, "Like" IDEA on Facebook here.
© 2014 by IDEA Health & Fitness Inc. All rights reserved. Reproduction without permission is strictly prohibited.
IDEA Newsletter Sign-up
|Extreme Interval Training
In this course you'll learn goal-focused intervals and over 50 dynamic exercises and drills to create extensive and intensive training formats.
|Cut to the Core
This is a raw, unedited video filmed live at the 2009 IDEA World Fitness Convention™. Cut to the Core is packed full of core-focused exercises that aim to improve the way you look, feel and live.
|September 2011 IDEA Fitness Journal Quiz 4: Plyometric Training
This continuing education quiz is an in-depth look at plyometric training. Plyometric exercises—jumping, bounding, hopping, arm pushing, and catching and throwing weighted objects such as machine balls—are movements that involve rapid eccentric and concentric muscle actions.